1 - A 50 year old female with end stage renal disease (ESRD) develops pulmonary tuberculosis. Which one of the following drugs should be used in a reduced dose ?
1 - A 50 year old female with end stage renal disease (ESRD) develops pulmonary tuberculosis. Which one of the following drugs should be used in a reduced dose ?
Ethambutol
2 - A common side effect associated with all NSAID drugs is_______________?
2 - A common side effect associated with all NSAID drugs is_______________?
Gastric irritation
3 - A Hemophiliac patient has rheumatold arthritis. Which drug might be prescribed to relieve the pain ?
3 - A Hemophiliac patient has rheumatold arthritis. Which drug might be prescribed to relieve the pain ?
Acetaminophen
4 - A paralyzing dose of succinylcholine initially elicits______________?
4 - A paralyzing dose of succinylcholine initially elicits______________?
Muscle fasciculation
5 - A patient is having bronchodilation, increased temperature, constipation and tachycardia. The tentative diagnosis is_______________?
5 - A patient is having bronchodilation, increased temperature, constipation and tachycardia. The tentative diagnosis is_______________?
Atropine poisoning
6 - A patient on 300 mg of aspirin will show all the following except________________?
6 - A patient on 300 mg of aspirin will show all the following except________________?
Irreversible inhibition of cyclooxygenase path way
7 - A patient taking beta-blocker preoperatively, at induction of anaesthesia with fentanyl. Which muscle relaxant should be avoided ?
7 - A patient taking beta-blocker preoperatively, at induction of anaesthesia with fentanyl. Which muscle relaxant should be avoided ?
Pancuronium
8 - A patient with grand mal epilepsy would likely be under treatment with_____________?
8 - A patient with grand mal epilepsy would likely be under treatment with_____________?
Phenytoin
9 - A patient with grandmal epilepsy would likely be under treatment with_______________?
9 - A patient with grandmal epilepsy would likely be under treatment with_______________?
Phenytoin
10 - A person with glaucoma should not receive________________?
10 - A person with glaucoma should not receive________________?
Antisialogogues
11 - A young lady talking rifampicin and OCP together become pregnant, most probable cause is____________?
11 - A young lady talking rifampicin and OCP together become pregnant, most probable cause is____________?
Rifampicin causes hepatic enzyme induction and increase metabolism of OCP's
12 - About heparin true is_____________?
12 - About heparin true is_____________?
Half-life is 90 min
13 - Action of Nitroglycerin is______________?
13 - Action of Nitroglycerin is______________?
Direct action on smooth muscle
14 - Activation of which of the following receptors would be expected to decrease anxiety_____________?
14 - Activation of which of the following receptors would be expected to decrease anxiety_____________?
GABA receptors
15 - Acute Barbiturate poisoning results in_______________?
15 - Acute Barbiturate poisoning results in_______________?
Respiratory failure
16 - Adrenaline is used in following EXCEPT______________?
16 - Adrenaline is used in following EXCEPT______________?
Both B & C
17 - Agents/Drugs which help in rapid coagulation of Blood_______________?
17 - Agents/Drugs which help in rapid coagulation of Blood_______________?
All of the above
18 - All are symptoms of opiate withdrawls except______________?
18 - All are symptoms of opiate withdrawls except______________?
Excessive speech
19 - All are true about metformin except_____________?
19 - All are true about metformin except_____________?
Used in decompensated heart failure
20 - All are true about nitric oxide, EXCEPT____________?
20 - All are true about nitric oxide, EXCEPT____________?
Acts via cAMP
21 - All are true of diazapenes except____________?
21 - All are true of diazapenes except____________?
Benzodiazepam is used in the long term treatment of psychic disorders
22 - All NSAIDs block cycloxygenase and____________?
22 - All NSAIDs block cycloxygenase and____________?
Prostaglandin synthesis
23 - All of the following are endogenous corticosteriods released by all adrenal cortex EXCEPT______________?
23 - All of the following are endogenous corticosteriods released by all adrenal cortex EXCEPT______________?
Dexamethsone
24 - All of the following are predominant arteriolar dilators except____________?
24 - All of the following are predominant arteriolar dilators except____________?
Nitrates
25 - All of the following are true about tolbutamide except____________?
25 - All of the following are true about tolbutamide except____________?
It is used in type-I diabetes mellitus
26 - All of the following decrease skeletal muscle tone by CNS effects except____________?
26 - All of the following decrease skeletal muscle tone by CNS effects except____________?
D-tubocurarin
27 - All of the following drugs are useful in treatment of hypertension except______________?
27 - All of the following drugs are useful in treatment of hypertension except______________?
Ephedrine
28 - All of the following glucocorticorticoids can be given by inhalation EXCEPT_______________?
28 - All of the following glucocorticorticoids can be given by inhalation EXCEPT_______________?
Dexamethasone
29 - All of the following have receptors which are transcription factors except____________?
29 - All of the following have receptors which are transcription factors except____________?
Insulin
30 - All of the following statements about opioids is correct except_____________?
30 - All of the following statements about opioids is correct except_____________?
Partial agonists are free from classic opioid adverse effects
31 - All of the following statements about pain are correct except_____________?
31 - All of the following statements about pain are correct except_____________?
Naloxane is a non-competitive antagonist and irreversibly opposes the opioids
32 - All of the given drugs are positive inotropes EXCEPT_____________?
32 - All of the given drugs are positive inotropes EXCEPT_____________?
Doxepin
33 - All of the given drugs may be useful in acute exacerbation of bronchial asthma EXCEPT_____________?
33 - All of the given drugs may be useful in acute exacerbation of bronchial asthma EXCEPT_____________?
Ipratropium
34 - All the following about antiemetic drugs are correct except_______________?
34 - All the following about antiemetic drugs are correct except_______________?
Ondastran may cause vomiting by effecting the cytotoxic antige receptors
35 - All the following drugs reduced the gastric acid secretion EXCEPT____________?
35 - All the following drugs reduced the gastric acid secretion EXCEPT____________?
Sucralfate
36 - Alpha blocker used as anti hypertensive agent_____________?
36 - Alpha blocker used as anti hypertensive agent_____________?
Prazosin
37 - Amitryptyline is a____________?
37 - Amitryptyline is a____________?
Tricyclic antidepressant
38 - Amyl nitrate is most commonly administered _________________?
38 - Amyl nitrate is most commonly administered _________________?
Sub lingually
39 - An antiepileptic drug used in petitmal epilepsy is______________?
39 - An antiepileptic drug used in petitmal epilepsy is______________?
Ethosuximide
40 - An anxiolytic, not interacting with GABA ergic system and used in generalized anxiety is______________?
40 - An anxiolytic, not interacting with GABA ergic system and used in generalized anxiety is______________?
Buspiron
41 - An attack of bronchial asthma is most likely to be triggered by________________?
41 - An attack of bronchial asthma is most likely to be triggered by________________?
Both A & B
42 - An attack of migraine can be easily terminated by___________?
42 - An attack of migraine can be easily terminated by___________?
Ergotamine
43 - An oral hypoglycemic agent is______________?
43 - An oral hypoglycemic agent is______________?
Glibeneclamide
44 - An untoward effect of that is common to all phenothiazines is______________?
44 - An untoward effect of that is common to all phenothiazines is______________?
Rigidity and tremor at rest, particularly with prolonged use
45 - Antagonist of morphine is_______________?
45 - Antagonist of morphine is_______________?
Naloxone
46 - Aspirin acts on which part of brain ?
46 - Aspirin acts on which part of brain ?
Substantia gelatinosa
47 - Aspirin causes___________?
47 - Aspirin causes___________?
Hypoprothrombinemia
48 - Aspirin is avoided in children with influenza infection because of association______________?
48 - Aspirin is avoided in children with influenza infection because of association______________?
Reye's syndrome
49 - Aspirin is contraindicated in______________?
49 - Aspirin is contraindicated in______________?
All of the above
50 - Aspirin is contraindicated in_______________?
50 - Aspirin is contraindicated in_______________?
Peptic ulcer
51 - Aspirin is used in treatment of Myocardial Infarction___________?
51 - Aspirin is used in treatment of Myocardial Infarction___________?
It inhibits thromboxanes
52 - Aspirin produces all of the following effects except_____________?
52 - Aspirin produces all of the following effects except_____________?
Constipation
53 - Aspirine cause_____________?
53 - Aspirine cause_____________?
Increase BT
54 - Aspirine is useful in all the following conditions EXCEPT_____________?
54 - Aspirine is useful in all the following conditions EXCEPT_____________?
Gout
55 - Atropine is used in______________?
55 - Atropine is used in______________?
Organophosphate poisoning
56 - Atypical Antipsychotic are all except______________?
56 - Atypical Antipsychotic are all except______________?
Thioridazone
57 - B- blocker with additional a-blocking property is____________?
57 - B- blocker with additional a-blocking property is____________?
Labetalol
58 - Benzodiazepine antagonist is________________?
58 - Benzodiazepine antagonist is________________?
Flumazenil
59 - BEnzodiazepines are true in___________________?
59 - BEnzodiazepines are true in___________________?
More safe than other sedatives when take in larger amounts
60 - Best and most effective drug to control convulsions in toxicity cases is______________?
60 - Best and most effective drug to control convulsions in toxicity cases is______________?
Diazepam
61 - Beta blockers are contraindicated in___________?
61 - Beta blockers are contraindicated in___________?
Cardiac failure
62 - Beta2 adrenergic receptor stimulating drugs are used in_______________?
62 - Beta2 adrenergic receptor stimulating drugs are used in_______________?
Bronchial asthma
63 - Birbiturates in pediatrics is_____________?
63 - Birbiturates in pediatrics is_____________?
Low safety
64 - Bleeding from the oral mucosa can be reduced by topical use of_______________?
64 - Bleeding from the oral mucosa can be reduced by topical use of_______________?
Epinephrine
65 - Blockers are used in all except_____________?
65 - Blockers are used in all except_____________?
Thyrotoxcosis
66 - Bradycardia is most commonly treated with which of the following drugs_____________?
66 - Bradycardia is most commonly treated with which of the following drugs_____________?
Atropine
67 - Bronchospasm can be precipitated by______________?
67 - Bronchospasm can be precipitated by______________?
propranolol
68 - Buprenorphine acts by following mechanism________________?
68 - Buprenorphine acts by following mechanism________________?
Mu receptor partial agnoist
69 - Carbamazepine is a type of___________?
69 - Carbamazepine is a type of___________?
Antidepressant
70 - Cloidogrel is an______________?
70 - Cloidogrel is an______________?
Antipalatelet
71 - Clotting time is most like to be prolonged by the administration of____________?
71 - Clotting time is most like to be prolonged by the administration of____________?
Acetyl salicylic acid
72 - Curare poisoning is characterised by________________?
72 - Curare poisoning is characterised by________________?
Hypotension
73 - Delay in blood coagulation results from_____________?
73 - Delay in blood coagulation results from_____________?
Heparin
74 - Diuretics cause loss of_______________?
74 - Diuretics cause loss of_______________?
Potassium
75 - Doalin pectrose is_____________?
75 - Doalin pectrose is_____________?
Anti diarroheal
76 - DOPA and 5-Hydroxytryptophan are clinically important because_____________?
76 - DOPA and 5-Hydroxytryptophan are clinically important because_____________?
They cross blood Brain Barriers
77 - Drug not requiring dose adjustment in renal disease is___________?
77 - Drug not requiring dose adjustment in renal disease is___________?
Calcium channel blocker
78 - Drug that does not cause sedation________________?
78 - Drug that does not cause sedation________________?
Buspirone
79 - Drug which causes gingival hyperplasia_____________?
79 - Drug which causes gingival hyperplasia_____________?
Both A & C
80 - Drug which is used to control status epilepticus is______________?
80 - Drug which is used to control status epilepticus is______________?
Diazepam
81 - Drugs causing hyperglycemia_______________?
81 - Drugs causing hyperglycemia_______________?
Glucocorticoids
82 - Drugs like barbiturates precipitate symptoms of prophyria because______________?
82 - Drugs like barbiturates precipitate symptoms of prophyria because______________?
They depress ALA synthase
83 - Dry mouth during antidepressant therapy is caused by blockade of______________?
83 - Dry mouth during antidepressant therapy is caused by blockade of______________?
Muscarinic acetylcholine receptors
84 - D-tubocurarine blocks the neuromuscular transmission by___________?
84 - D-tubocurarine blocks the neuromuscular transmission by___________?
Blocking acetylcholine receptors
85 - Each of the following is correct for the treatment of Diarrhoea except_______________?
85 - Each of the following is correct for the treatment of Diarrhoea except_______________?
Diphenoxylate may cause respiratory depression on administration
86 - Excessive bleeding due to heparin overdose is controlled by______________?
86 - Excessive bleeding due to heparin overdose is controlled by______________?
Protamine sultate
87 - Fellypressin is a_______________?
87 - Fellypressin is a_______________?
Vaso constrictor
88 - Folic acid deficiency occurs in______________?
88 - Folic acid deficiency occurs in______________?
Phenytoin
89 - Following analgesic combination should be avoided ?
89 - Following analgesic combination should be avoided ?
Ibuprofen and DIclofenac
90 - Following inhibits Cytochrome P450_____________?
90 - Following inhibits Cytochrome P450_____________?
Cimetidine
91 - Gastric irritation is minimum with one of the following non-steroidal anti inflammatory drugs_____________?
91 - Gastric irritation is minimum with one of the following non-steroidal anti inflammatory drugs_____________?
Meloxicam
92 - Heparin, apart from releasing lypoprotein lipase in the blood exerts its anti-coagulant action by____________?
92 - Heparin, apart from releasing lypoprotein lipase in the blood exerts its anti-coagulant action by____________?
Inhibiting thrombin synthesis
93 - Heroin, an addict drug contains______________?
93 - Heroin, an addict drug contains______________?
Acetyl morphine
94 - Hypokalemia is seen in therapy with____________?
94 - Hypokalemia is seen in therapy with____________?
Digitalis
95 - Ibuprofen is contraindicated in_______________?
95 - Ibuprofen is contraindicated in_______________?
patients having asthma
96 - Identify the factors which decrease the effect of Oral anticoagulants_______________?
96 - Identify the factors which decrease the effect of Oral anticoagulants_______________?
Both A & B
97 - If patient is given Noradrenaline what will happen_______________?
97 - If patient is given Noradrenaline what will happen_______________?
Cause increase in B.P, due to its action on Beta receptors only
98 - In treating Xerostomia, Which of the following might be prescribed ?
98 - In treating Xerostomia, Which of the following might be prescribed ?
Neostigmine
99 - In which of the following categories are ephedrine, tyramine and emphetamine classified________________?
99 - In which of the following categories are ephedrine, tyramine and emphetamine classified________________?
Indirect acting sympathomimetics
100 - Indirect sympathomimetics can_______________?
100 - Indirect sympathomimetics can_______________?
Both of the above
101 - INFLIXIMAB (systemic) is used in_____________?
101 - INFLIXIMAB (systemic) is used in_____________?
All of the above
102 - Ipratropium bromide is used for_____________?
102 - Ipratropium bromide is used for_____________?
Bronchial asthma
103 - Isosorbide 5 – mononitrate is preferred because____________?
103 - Isosorbide 5 – mononitrate is preferred because____________?
Longer duration of action
104 - IV ultrashort acting barbiturate_____________?
104 - IV ultrashort acting barbiturate_____________?
Thiopentone
105 - Less gastrointestinal bleed is seen in the following NSAID_______________?
105 - Less gastrointestinal bleed is seen in the following NSAID_______________?
C0X2 specific inhibitors
106 - Long acting beta – 2 agonist ?
106 - Long acting beta – 2 agonist ?
Salmeterol
107 - Magnesium and Aluminium are added in Antacid because_____________?
107 - Magnesium and Aluminium are added in Antacid because_____________?
Mg Causes Diarrhoea, Al Causes Constipation
108 - Mechanism of action of nifidipine is_____________?
108 - Mechanism of action of nifidipine is_____________?
It has a prominent smooth muscle relaxant action causes arteolar dilation leading to fall in blood pressure
109 - Mode of action of sulphonyl ureas includes all the following except______________?
109 - Mode of action of sulphonyl ureas includes all the following except______________?
Decreasing Glucose absorption from the qut
110 - Morphine a powerful opioid analgesic drug should be avoided in all the following conditions except____________?
110 - Morphine a powerful opioid analgesic drug should be avoided in all the following conditions except____________?
A & C
111 - Morphine is a_____________?
111 - Morphine is a_____________?
Both A & B
112 - Morphine is contraindicated in all of the following except_______________?
112 - Morphine is contraindicated in all of the following except_______________?
Pulmonary oedema
113 - Morphine withdrawal is characterized by all EXCEPT_____________?
113 - Morphine withdrawal is characterized by all EXCEPT_____________?
Miosis
114 - Narcotic overdose can be antagonized by______________?
114 - Narcotic overdose can be antagonized by______________?
Naloxane
115 - Neuromuscular blocking agent with duration of onset of action less than 2 minutes is_________________?
115 - Neuromuscular blocking agent with duration of onset of action less than 2 minutes is_________________?
Succinyl choline
116 - Neusea and vomiting that are associated with administration of opioid analgesic is the result of stimulation of the_____________?
116 - Neusea and vomiting that are associated with administration of opioid analgesic is the result of stimulation of the_____________?
Chemoreceptor trigger zone (CTZ)
117 - NSAID which undergoes enterohepatic circulation______________?
117 - NSAID which undergoes enterohepatic circulation______________?
Piroxicam
118 - NSAID's have adverse effect on________________?
118 - NSAID's have adverse effect on________________?
Stomach
119 - Omeprazol is used in the treatment of____________?
119 - Omeprazol is used in the treatment of____________?
Peptic Ulcer
120 - Omeprazole is a_____________?
120 - Omeprazole is a_____________?
Proton pump inhibitor
121 - One of the benzodiazepines (BDZ) comparatively safe in pregnancy is (Category-B) ?
121 - One of the benzodiazepines (BDZ) comparatively safe in pregnancy is (Category-B) ?
Lorazepam
122 - One of the following is not an antiemetic_____________?
122 - One of the following is not an antiemetic_____________?
Digitoxin
123 - One of the obious consequences of alchol ( ethenol), ingestion in many individual is facial flushing and increased heart rate triggered off by alcohol getting metabolized to______________?
123 - One of the obious consequences of alchol ( ethenol), ingestion in many individual is facial flushing and increased heart rate triggered off by alcohol getting metabolized to______________?
Acetaldehyde
124 - Paracetamol is contraindicated in_______________?
124 - Paracetamol is contraindicated in_______________?
A & B
125 - Phenothiazines are used to____________?
125 - Phenothiazines are used to____________?
Alter psychotic behaviour
126 - Phenytoin is associated with_____________?
126 - Phenytoin is associated with_____________?
Folic acid deficiency
127 - Platelet aggregation in inhibited by all except_______________?
127 - Platelet aggregation in inhibited by all except_______________?
Phenobarbitone
128 - Pregnant patient can be safely given______________?
128 - Pregnant patient can be safely given______________?
Paracetamol
129 - Prolonged use of aspirin causes_______________?
129 - Prolonged use of aspirin causes_______________?
Hypoprothrombinemia
130 - Prolonged use of aspirin leads to______________?
130 - Prolonged use of aspirin leads to______________?
A & B
131 - Quindine is used to treat______________?
131 - Quindine is used to treat______________?
Atrial fibrillation
132 - Quinine is obtained from CINCHONA________________?
132 - Quinine is obtained from CINCHONA________________?
Bark
133 - Rebound phenomenon is most commonly seen with use of_________________?
133 - Rebound phenomenon is most commonly seen with use of_________________?
Epinephrine
134 - Respiratory depression is seen with_____________?
134 - Respiratory depression is seen with_____________?
Synthetic narcotics
135 - Role of Heparin_____________?
135 - Role of Heparin_____________?
Prevents prothrombin conversion to thrombin
136 - Salbutamol is used in_____________?
136 - Salbutamol is used in_____________?
Bronchial asthma
137 - Salicylate administration is contraindicated in pregnancy because_______________?
137 - Salicylate administration is contraindicated in pregnancy because_______________?
All of these
138 - Salicylate overdose in children causes_______________?
138 - Salicylate overdose in children causes_______________?
Rye's syndrome
139 - Scopolamine helps in________________?
139 - Scopolamine helps in________________?
A & C
140 - Short-acting non-depolarising muscle relaxant is________________?
140 - Short-acting non-depolarising muscle relaxant is________________?
Mivacurum
141 - Shortest acting opioid analgesic is______________?
141 - Shortest acting opioid analgesic is______________?
Remifentanil
142 - Sialogouges are______________?
142 - Sialogouges are______________?
Increases salivary secretions
143 - Steroids________________?
143 - Steroids________________?
Steroids reduce the rate of repair of tissues thus delays the healing
144 - Succinylcholine is a/an______________?
144 - Succinylcholine is a/an______________?
None of the above
145 - Succinylcholine prevents bronchospasm by______________?
145 - Succinylcholine prevents bronchospasm by______________?
Depolarising block
146 - The anticoagulant action of Warfarin is potentiated by all except_____________?
146 - The anticoagulant action of Warfarin is potentiated by all except_____________?
B & C
147 - The anticogulant of choice during pregnancy is______________?
147 - The anticogulant of choice during pregnancy is______________?
Heparin
148 - The anti-inflammatory analgesic drug the causes least gastrointestinal symptoms is______________?
148 - The anti-inflammatory analgesic drug the causes least gastrointestinal symptoms is______________?
Paracetamol
149 - The beneficial effect of drug neostigmine in the treatment of Myasthenia gravis is due to the action____________?
149 - The beneficial effect of drug neostigmine in the treatment of Myasthenia gravis is due to the action____________?
It inhibits the action of cholinesterase
150 - The drug which activates plasma antithrombin -III for its anticogulant action is____________?
150 - The drug which activates plasma antithrombin -III for its anticogulant action is____________?
Heparin
151 - The drug which is contraindicated in haemophilla is_________________?
151 - The drug which is contraindicated in haemophilla is_________________?
Aspirin
152 - The Ethyl alcohol (Ethanol) is more effective when mixed with water and used as_____________?
152 - The Ethyl alcohol (Ethanol) is more effective when mixed with water and used as_____________?
60 to 70 percent
153 - The first choice of drug for patitmal seizure is________________?
153 - The first choice of drug for patitmal seizure is________________?
None of the above
154 - The following drugs are useful in hypertension except_____________?
154 - The following drugs are useful in hypertension except_____________?
Pentoxifyline
155 - The highest risk associated with use of oral contraceptives in________________?
155 - The highest risk associated with use of oral contraceptives in________________?
Thromboembolic disorders
156 - The intramuscular administration of 0.6 mg of atropine sulphate to a 50 kg adult may produce all of the following effects except________________?
156 - The intramuscular administration of 0.6 mg of atropine sulphate to a 50 kg adult may produce all of the following effects except________________?
Bradycardia
157 - The mechanism of action of sodium nitroprusside is_____________?
157 - The mechanism of action of sodium nitroprusside is_____________?
Direct Vasodilator
158 - The most prominent toxic effect associated with acetominophen use is______________?
158 - The most prominent toxic effect associated with acetominophen use is______________?
Hepatic necrosis
159 - The muscle relaxant effect of succinylcholine lasts for______________?
159 - The muscle relaxant effect of succinylcholine lasts for______________?
3-5 min
160 - The potent anti arrhythmic drug which has little negative ionotropic effect valuable in patients with poor left ventricular function_____________?
160 - The potent anti arrhythmic drug which has little negative ionotropic effect valuable in patients with poor left ventricular function_____________?
Digoxin
161 - The principle central action of caffeine is on the________________?
161 - The principle central action of caffeine is on the________________?
Cerebral cortex
162 - The principle therapeutic action of the glucocorticoid is________________?
162 - The principle therapeutic action of the glucocorticoid is________________?
Anti-inflammatory
163 - The rate of injection of intravenous Valium is_______________?
163 - The rate of injection of intravenous Valium is_______________?
1 ml / min
164 - The statement Not true of Selective Cox – 2 inhibitor is________________?
164 - The statement Not true of Selective Cox – 2 inhibitor is________________?
Safe in patients with renal insufficiency
165 - The toxic effect of Beta receptor antagonists includes all the following EXCEPT____________?
165 - The toxic effect of Beta receptor antagonists includes all the following EXCEPT____________?
Precipitate migrainic effect
166 - Therapeutic uses of a – adrenoceptor blockers include all of the following EXCEPT______________?
166 - Therapeutic uses of a – adrenoceptor blockers include all of the following EXCEPT______________?
Amxiety
167 - Thiopentone action is terminated by______________?
167 - Thiopentone action is terminated by______________?
Redistribution
168 - Thyroid storm can be treated by all the following drugs EXCEPT______________?
168 - Thyroid storm can be treated by all the following drugs EXCEPT______________?
Aspirin
169 - Triflusal is a___________________?
169 - Triflusal is a___________________?
Antiplatelet drug
170 - True about use of midazolam over diazepam is sedation in all except ?
170 - True about use of midazolam over diazepam is sedation in all except ?
Binds to benzodiazepine receptors with 3-4 time more avidly
171 - various insulin preparations useful in the treatment of diabetes mellitus differ primarily in______________?
171 - various insulin preparations useful in the treatment of diabetes mellitus differ primarily in______________?
Onset and duration of action
172 - Verril's sign is seen in_________________?
172 - Verril's sign is seen in_________________?
Diazepam administration
173 - Warfarin therapy is prolonged by all except______________?
173 - Warfarin therapy is prolonged by all except______________?
Rifampicin
174 - Which among the following is a pure antagonist of opioid receptors ?
174 - Which among the following is a pure antagonist of opioid receptors ?
Natrexone
175 - Which among the following may be used as a sedatives hypnotic ?
175 - Which among the following may be used as a sedatives hypnotic ?
Zolpiden
176 - Which among the following Not a pharmacological action of opioids______________?
176 - Which among the following Not a pharmacological action of opioids______________?
Anti-emesis
177 - Which is NOT a 2nd generation antihistaminic ?
177 - Which is NOT a 2nd generation antihistaminic ?
Cyclizine
178 - Which is not antiemetic ?
178 - Which is not antiemetic ?
Phenazocine
179 - Which of the following anti inflammatory drug is a COX-2 inhibitor_____________?
179 - Which of the following anti inflammatory drug is a COX-2 inhibitor_____________?
Rofecoxib
180 - Which of the following anti-epileptic agents causes the reversible side-effect of gingival hyperplasia ?
180 - Which of the following anti-epileptic agents causes the reversible side-effect of gingival hyperplasia ?
None of the above
181 - Which of the following antihypertensive agents in most likely to cause an exaggerated response to an injected catecholamine_____________?
181 - Which of the following antihypertensive agents in most likely to cause an exaggerated response to an injected catecholamine_____________?
Gauanethidine
182 - Which of the following can be given safely to a patient of congestive heart failure________________?
182 - Which of the following can be given safely to a patient of congestive heart failure________________?
Paracetamol
183 - Which of the following cardiac depressants is contraindicated in a patient with cardiac arrhythmia____________?
183 - Which of the following cardiac depressants is contraindicated in a patient with cardiac arrhythmia____________?
Quinidine
184 - Which of the following combination of iron can be given both IM and IV____________?
184 - Which of the following combination of iron can be given both IM and IV____________?
Iron dextran
185 - Which of the following drug induces parkinsonism ?
185 - Which of the following drug induces parkinsonism ?
Chlorpromazine
186 - Which of the following drug is used to counter act the gastric irritation produced by administration of NSAID_______________?
186 - Which of the following drug is used to counter act the gastric irritation produced by administration of NSAID_______________?
Misoprostol
187 - Which of the following drugs can be given safely to a patient with renal disease ?
187 - Which of the following drugs can be given safely to a patient with renal disease ?
Diazepam
188 - Which of the following drugs causes extra pyramidal symptoms_____________?
188 - Which of the following drugs causes extra pyramidal symptoms_____________?
Phenothiazines
189 - Which of the following drugs is currently widely used in treating opioid dependent individuals?
189 - Which of the following drugs is currently widely used in treating opioid dependent individuals?
Methadone
190 - Which of the following drugs is least efficacious in the treatment of cemporal lobe epilepsy ?
190 - Which of the following drugs is least efficacious in the treatment of cemporal lobe epilepsy ?
Primidone
191 - Which of the following drugs is not hypoglycemic?
191 - Which of the following drugs is not hypoglycemic?
Glibenclamide
192 - Which of the following drugs is used therapeutically during allergic conditions ?
192 - Which of the following drugs is used therapeutically during allergic conditions ?
Epinephrine
193 - Which of the following drugs is used to treat both diabetes mellitus and diabetes insipidus_____________?
193 - Which of the following drugs is used to treat both diabetes mellitus and diabetes insipidus_____________?
Chlorpropamide
194 - Which of the following drugs undergoes “Hoffmann elimination" ?
194 - Which of the following drugs undergoes “Hoffmann elimination" ?
Atracurium
195 - Which of the following general anesthetics is given by intravenous route ?
195 - Which of the following general anesthetics is given by intravenous route ?
Propofol
196 - Which of the following is a muscle relaxant_________________?
196 - Which of the following is a muscle relaxant_________________?
Pentazocine
197 - Which of the following is a non steroidal anti inflammatory agent with a tendency to produce blood dyscrasias ?
197 - Which of the following is a non steroidal anti inflammatory agent with a tendency to produce blood dyscrasias ?
B & C
198 - Which of the following is a nonsteroldad anti inflammatory agent with a tendency to produce blood dyscriasis ?
198 - Which of the following is a nonsteroldad anti inflammatory agent with a tendency to produce blood dyscriasis ?
Indomathecin (indocin)
199 - Which of the following is a peripherally acting muscle relaxant______________?
199 - Which of the following is a peripherally acting muscle relaxant______________?
Succinyl choline
200 - Which of the following is a protective drug in the management of gastric and duodenal ulcers ?
200 - Which of the following is a protective drug in the management of gastric and duodenal ulcers ?
Carbenoxolone
201 - Which of the following is a short acting barbiturate ?
201 - Which of the following is a short acting barbiturate ?
Secobarbital
202 - Which of the following is a vosoconstrictor______________?
202 - Which of the following is a vosoconstrictor______________?
None of the above
203 - Which of the following is an ACE inhibitor ?
203 - Which of the following is an ACE inhibitor ?
Coptopril
204 - Which of the following is an irreversible side enact resulting from long term administration of phenothiazline antipsychotics__________________?
204 - Which of the following is an irreversible side enact resulting from long term administration of phenothiazline antipsychotics__________________?
B & C
205 - Which of the following is antiasthmatic_____________?
205 - Which of the following is antiasthmatic_____________?
Salbutamol
206 - Which of the following is not a contraindication in the therapy with opioids_____________?
206 - Which of the following is not a contraindication in the therapy with opioids_____________?
Use in severe constant pain
207 - Which of the following is not an antimigraine agent ?
207 - Which of the following is not an antimigraine agent ?
Zonisamide
208 - Which of the following is NOT an important/frequent/well-known manifestation of an adverse drug reaction ?
208 - Which of the following is NOT an important/frequent/well-known manifestation of an adverse drug reaction ?
Leukaemia
209 - Which of the following is not caused by Frusemide____________?
209 - Which of the following is not caused by Frusemide____________?
Hypercalcemia
210 - Which of the following is not true about ACE inhibitors ?
210 - Which of the following is not true about ACE inhibitors ?
Postural hypotension is seen
211 - Which of the following is true about parasympathetic nervous system ?
211 - Which of the following is true about parasympathetic nervous system ?
Ach is transmitter at both pre & post synaptic junction
212 - Which of the following opioids is not given intrathecally ?
212 - Which of the following opioids is not given intrathecally ?
Remifentanil
213 - Which of the following receptors is activated by acetylcholine and blocked by atropine______________?
213 - Which of the following receptors is activated by acetylcholine and blocked by atropine______________?
Muscarinic
214 - Which of the following statements is not correct regarding warfarin_____________?
214 - Which of the following statements is not correct regarding warfarin_____________?
In a racemic mixture the R form is four times more active than the S form
215 - Which of the following statements regarding nitroglycerin is true ?
215 - Which of the following statements regarding nitroglycerin is true ?
All of the above
216 - Which of the following sympathominetic agents is the most bronchodilator_____________?
216 - Which of the following sympathominetic agents is the most bronchodilator_____________?
Isoproterenol
217 - Which of the following synthetic sterioid shows predominantly mineralocorticoid action ?
217 - Which of the following synthetic sterioid shows predominantly mineralocorticoid action ?
Fludrocortisone
218 - Which one is not converted to an active metabolite ?
218 - Which one is not converted to an active metabolite ?
Lisinopril
219 - Which one of the anti hypertensives is contraindicated in pregnancy ?
219 - Which one of the anti hypertensives is contraindicated in pregnancy ?
Enlapril
220 - Which one of the following agents/ drugs is of no value in the post operative care of the hemophiliac patient ?
220 - Which one of the following agents/ drugs is of no value in the post operative care of the hemophiliac patient ?
Clopidogrel
221 - Which one of the following can be blocked by atropine ?
221 - Which one of the following can be blocked by atropine ?
Decreased blood pleasure caused by hexamethonium
222 - Which one of the following does NOT act by increasing insulin secretion______________?
222 - Which one of the following does NOT act by increasing insulin secretion______________?
Biguanide
223 - Which one of the following drugs has been shown to offer protection from gastric aspiration syndrome in a patient with symptoms of reflex ?
223 - Which one of the following drugs has been shown to offer protection from gastric aspiration syndrome in a patient with symptoms of reflex ?
Metoclopramide
224 - Which one of the following drugs is most commonly employed in an attack of angina pectoris ?
224 - Which one of the following drugs is most commonly employed in an attack of angina pectoris ?
Nitroglycerina
225 - Which one of the following drugs is not a non depolarizing competitive neuromuscular blocker ?
225 - Which one of the following drugs is not a non depolarizing competitive neuromuscular blocker ?
Decamethonium
226 - Which one of the following drugs is not a reversible anticholinesterase drug ?
226 - Which one of the following drugs is not a reversible anticholinesterase drug ?
Carbaryl
227 - Which one of the following drugs is not contraindicated in bronchial asthma ?
227 - Which one of the following drugs is not contraindicated in bronchial asthma ?
Nitroglycerine
228 - Which one of the following is NOT an ergot alkaloids_____________?
228 - Which one of the following is NOT an ergot alkaloids_____________?
Ketanserin
229 - Which one of the following is Not true of angiotensin converting enzyme (ACE) inhibitor____________?
229 - Which one of the following is Not true of angiotensin converting enzyme (ACE) inhibitor____________?
Contraindicated in diabetic nephropathy
230 - Which one of the following muscle relaxant has the maximum duration of action ?
230 - Which one of the following muscle relaxant has the maximum duration of action ?
Doxacurium
231 - Which one of the following NSAIDs has adverse effects on liver ?
231 - Which one of the following NSAIDs has adverse effects on liver ?
Acetaminophen
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