Home Genetics Genetics Most Important MCQs: Set#. 2

Genetics Most Important MCQs: Set#. 2

201 - Contractile protein/proteins

Both a and b

202 - CRISPR RNA's one end binds to CRISPR- Cas nuclease and other bind to

Gene of interest

203 - CRISPR-Cas is used to modify

Gene

204 - Cultivated autopolyploids of wheat

Both a and b

205 - Darwin's theory of evolution was criticised due to lack of

Genetic basis of variation

206 - Data from human genome project indicate that the X chromosome has at least___________genes

900

207 - Data from human genome project indicate that the y chromosome has at least___________genes

75

208 - Deep red color of urine is symptom of

Porphyria variegata

209 - Defective mitochondria play a role in _________

Aging

210 - Diamond-Blackfan anemia is a rare,dominant disorder characterized by________malfunction

Bone marrow

211 - Digestion of chromatin by certain endonucleases, yields DNA fragments that are about _____ base pairs in length or multiples thereof

200

212 - Diploid bananas contain hard _________

Seeds

213 - Discontinuous DNA synthesis was fierst presented by

Okazaki

214 - Division of cytoplasm is called

Cytokinesis

215 - Division of nucleus is called

Karyokinesis

216 - DNA and RNA absorb UV light most strongly at

260 nm

217 - DNA as atransforming agent was proved by

Avery

218 - DNA as heredity material was experimentall proved by_________and cowoerkers in 1944

Avery

219 - DNA as heredity material was proved by experiments in_______

1944

220 - DNA associated proteins, histones are___________charged

Positively

221 - DNA associated proteins, nonhistones are___________charged

Less Positively

222 - DNA binding protein in bacteria

Both a and b

223 - DNA helicase in bacteria is made up of multiple copies of_____________

DnaB

224 - DNA is found in

All of these

225 - DNA polymeraseIII requires _________ to start DNA synthesis

Primer

226 - DNA serves as the genetic material in all living organisms on earth except some __________

Viruses

227 - DNA was first studied in 1869 by a Swiss chemist______

Miescher

228 - DNA__________is found exclusively in mitochondria

Polymerase gamma

229 - Domestication of animals started between_______B.C

8000 to 1000

230 - Double helix structure of DNA was proposed by

Watson

231 - Down syndrome in human is example of

Trisomy

232 - Down syndrome in human occur 1 in every________births

800

233 - Down syndrome is not

Inherited

234 - Duchene muscular dystrophy in human is ________trait

X-linked

235 - Duchene muscular dystrophy in human is often fatal in the early

20s

236 - Duchenne muscular dystrophy (DMD) can be cured by

Exon skipping

237 - During complete linkage only______________gametes are produced

Both a and b

238 - During _______________ the centromere are positioned on the equatorial plate

MetaphaseII

239 - During Bacteriophage life cycle about_______viruses are constructed in one cycle

200

240 - During conjugation, _________of plasmids of donor bactreium is transferred to recipient bacterium

Single strand

241 - During elongation of translation, _________binds GTP, brings aminoacyl tRNA to the A site of the ribosome

EF-Tu

242 - During elongation of translation,___________ regulate EF-Tu activity

EF-Ts

243 - During elongation of translation,___________ stimulates translocation; GTP dependent

EF-G

244 - During gamete formation loop formation occurs between homologous chromosomes having

All of these

245 - During Garrod time's, ___________was/were used in place of genes

Both a and b

246 - During initiation of translation,_______ binds to 30 S subunit and preventing it from associating with the 50S subunit prematurely

IF3

247 - During initiation of translation,________ binds to the initiator fMet-tRNA and transfer it to the P site of the 30S-mRNA complex

IF2

248 - During initiation of translation,__________ binds to 30 S subunit and prevent aminacyl tRNA from binding to the A site prematurely

IF1

249 - During meoisis, a____________ number of cross over events occur in each tetrad

limited

250 - During mitosis nuclear membrane disappears in

prophase

251 - During mitosis the condensation of chromosomes occurs in

prophase

252 - During mitosis the splitting of sister chromatids occurs in

prophase

253 - During mixed infection of mutant phages, the production of wild type phage is called

Complementation

254 - During modification of RNA transcripts in eukaryotes, the__________are spliced

Introns

255 - During posttranslational modification of proteins , trimming in polypeptide chain occur in____________

Insulin

256 - During posttranslational modification of proteins the_______residue isremoved enzymatically in bacteria

Formylmethionine

257 - During posttranslational modification of proteins, addition of __________may occur

Both a and b

258 - During prophase II each dyad is composed of ______pair/pairs of sister chromateds attached with common centromeric region

1

259 - During synkaryon, most of the chromosomes of one nucleus are gradually

Lost

260 - During termination of translation,___________ behave like RF1; specific for UGA and UAA

RF2

261 - During termination of translation,___________ catalyses release of the polypeptide chain from tRNA and dissociation of the translocation complex

RF1

262 - During termination of translation,___________ stimulates other releasing factors

RF3

263 - During the first________minutes, no genetic recombination is detected in bacterial conjugation

8

264 - During_________each daughter cell receive equal amount of cytoplasm

Spermatogenesis

265 - During_________each daughter cell receive unequal amount of cytoplasm

Oogenesis

266 - Dystrophin gene contain ________kb

2400

267 - Each chromosome become monad in

TelophaseII

268 - Each chromosome contains a constricted region called

Centromere

269 - Each complete turn of the DNA double helix contains__________bases

10

270 - Each complete turn of the DNA double helix is_________angstrom

34

271 - Each diploid organism contains two copies of each gene as consequence of

Biparental inheritance

272 - Each micronucleoli of oocyte is equivalent to

NOR(Nuclear organizer region)

273 - Each nucleosome consists of about __________base pairs of DNA wraped around eight histone protein molecules

200

274 - Each nucleosome measures about_________nm at its longest point

11

275 - Each polypeptide has amino group at one end and __________at the other end

Carboxyl group

276 - Each polytene chromosome is ___________µm long

200-600

277 - Each strain of Diplococcus may be one of dozens different types of _________

Serotypes

278 - Each strain of Diplococcus may be one of______different types of serotypes

Dozens

279 - Each synapsed pair of homologs is intially called

Bivalent

280 - Each word within mRNA consists of _________ribonucleotide letters

3

281 - Edwards is ____________trisomy

47,18

282 - Electrophoretic separation of nucleic acids is at heart of a variety of other techniques such as

Both a and b

283 - Endosymbionts theory was proposed by

Margulis

284 - Enlarge breast and rounded hips are characters of

Klinefelter syndrome

285 - Envieonmental factor/factors which can modify gene expression

All of these

286 - Epicanthic fold in each eye is characteristic of

Down syndrome

287 - Episomes are __________ which can integrate with bacterial chromosome

Plasmids

288 - Eukaryotes chromosome contains________replication origin/origins

Multiple

289 - Evening promose produces ________ flowers when grown at 18áµ’C

White

290 - Evening promose produces ________ flowers when grown at 23áµ’C

Red

291 - Example of Robertsonian translocation

Down syndrome

292 - except for_________,each member of human species exhibits a distinctve set of traits

Identical twins

293 - ExPASy(Expert Protein Analysis System) was hosted by the _______Institute of Bioinformatics

Swiss

294 - Exponential growth rate of bacteria

log phase

295 - Extranuclear inheretance is also known as

All of these

296 - F- bacteria are

Recipient

297 - F factor in bacteria contains about___________genes

40

298 - F factor consists of a circular, double stranded _______

DNA

299 - F factor in bacteria contains about___________nucleotide pairs

100000

300 - F factor is about_________ of the bacterial chromosome

2

301 - F+ bacteria are

Donor

302 - Fertility factor(F factor) is found in_____________bacteria

F+

303 - Fewer than______percent of the progeny of parents heterozygous for a reciprocal translocation survive

50

304 - First x-chromosome was identified in the somatic cells of female butterfly Protenor by

Edmund B.Wilson

305 - For gene mapping, crossing over is necessary in Eukaryotes and ____________in Bacteria

All of these

306 - For successful cross, the genotype of the organism must be_________at all loci

Heterozygous

307 - For the insertion of gene of interest into carrier DNA molecules called

Vector

308 - Found in connective tissues

Collagen

309 - Found in hair of orhanisms

Keratin

310 - GC rich hairpin secondary structure is immediately followed by a string of ________residues

Uracil

311 - GC rich Hairpin secondary structure is stable with _______rich nucleotides

GC

312 - GenBank contains more than_______billon base pairs of sequence data

220

313 - Gene activity is correlated ______________of histones

All of these

314 - Gene redundancy or gene amplification in oocytes is needed to constuct_________

Ribosome

315 - Genes expression___________with increase in ploidy

Both a and b

316 - Genes which are present on both X and Y chromosomes are called_______________genes

Pseudoautosomal

317 - Genetic code is

All of these

318 - Genetic markers are___________portions of specific chromosome

identifiable

319 - Genetics problems are solved by

Punnett square

320 - Giant lampbrush chromosomes are _____________ chromosomes

Meiotic

321 - Giant lampbrush chromosomes are often extended to lengths of __________µm

500-800

322 - Giant lampbrush chromosomes were first observed by

Flemming

323 - Giant polytene chromosomes are found in various tissue/tissues such as_______________in the larvae of some flies

All of these

324 - Giant polytene chromosomes are found in various tissues of in the

All of these

325 - Giant polytene chromosomes were observed by

Balbiani

326 - Giant size chromosomes

Both a and b

327 - Gonadal ridges arises by the _________week of gestation in human

5

328 - G-rich single stranded tails are capable of interacting with upstream sequences within the tail, creating a loop called

t-loop

329 - Group II introns are found in

All of these

330 - GU dinucleotide sequence of snRNAs also called as

Splice donor

331 - Guanine forms_______hydrogen bond with cytosine

3

332 - H substance is present in blood group

All of these

333 - H1 histone proteins are _____________rich

Lysine

334 - H2A histone proteins are _____________rich

Slightly Lysine

335 - H2B histone proteins are _____________rich

Slightly Lysine

336 - H3 histone proteins are _____________rich

Arginine

337 - H4 histone proteins are _____________rich

Arginine

338 - Hairpin secondary structure is formed at the __________of transcription

End

339 - Har Gobind Khorana used______________to synthesize artificial RNA

RNA copolymers

340 - Hemophilia A and B in human are ________traits

X-linked

341 - Hemophilia A gene is located on________chromosome

X

342 - Hershey and Chase to prove that DNA is heridity material worked with

Viruses

343 - Hershey and Chase used___________to prove that DNA is heredity material

Bacteriophage

344 - Heterochromosome in sperm of gross hopper was identified by

McClung

345 - High temperature in ___________ZZ (Pogona vitticeps) can cause sex reversal

Male

346 - Highly repetitive and moderately repetitive DNA of human genome comprise about___________percent

50

347 - Histones contain positively charged amino acid/acids

Both a and b

348 - Historically, the term amber was used to distinguish mutations producing termination codons

UAG

349 - Historically, the term ochre was used to distinguish mutations producing termination codons

UAA

350 - Historically, the term opal was used to distinguish mutations producing termination codons

UGA

351 - Homozygous recessive yellow coat colored mice die_________

Before birth

352 - Horizontal gene tranfer is applied between the member of _____________ species

Both a and b

353 - Horn formation in certain breeds of sheep is_______________trait

Sex influenced inheretance

354 - Host range(h)strain of viruses were discovered by

Salvador Luria

355 - How many types of mapping are commonly used

2

356 - How much Barr body will arise in 47, XXX females

2

357 - How much Barr body will arise in 48, XXXX females

3

358 - How much Barr body will arise in Klinefelter 47, XXY

1

359 - How much Barr body will arise in Turner 45, X females

0

360 - Human mitochondria contain only_________tRNA species

22

361 - Human mtDNA has_______ essential genes

37

362 - Human sex chromosomes were identified by

Joe Hin Tjio

363 - Human sex chromosomes were identified by Joe Hin Tjio in____________

1956

364 - Human traits are studies through

Pedigree

365 - Hyperchromic shift in DNA is Characterized by

All of these

366 - β-globin chain of hemoglobin contains_______ amino acids

146

367 - Identification of gene locus and distance between genes is called

Gene linkage

368 - If differentially staining pattern is produced along mitotic chromosomes is called

G-banding

369 - If 13 percent of flies within mutant genotype show the wild type appearance, the penetrance of mutant genotype will be

87

370 - If a genome has multiple copies of different set of chromosomes

Allopolyploidy

371 - If a genome has multiple copies of same set of chromosomes

Autopolyploidy

372 - If A represent haploid set of chromosome, AAAAAA will be

Hexaploid

373 - If centromere is located at the end of chromosome______is called

Telocentric

374 - If centromere is located close to end of chromosome______is called

Acrocentric

375 - If centromere is located in the middle of chromosome______is called

Metacentric

376 - If centromere is located near the middle of chromosome______is called

Submetacentric

377 - If DNA is subjected to heat

All of these

378 - If fewer DCOs than expected occur, interference will be

Possitive

379 - If more DCOs than expected occur, interference will be

Negative

380 - If only centromeric regions of mitotic chromosomes took up the stain is called

C-banding

381 - If only one member of a homologous pair of chromosomes has an inverted segment

Inversion heterozygote

382 - If petite mutant is crossed with wild type Sacharomyces cervisiae and progeny is petite type and wild type, the petite is__________

Segregational petite

383 - If petite mutant is crossed with wild type Sacharomyces cervisiae and progeny is petite type, the petite is__________

Suppressive petite

384 - If petite mutant is crossed with wild type Sacharomyces cervisiae and progeny is wild type, the petite is__________

Neutral petite

385 - If the centromere is a part of inverted segment

Pericentric inversion

386 - If the centromere is not a part of inverted segment

Paracentric inversion

387 - If the coefficient of coincidence is 0.804 what wil be the interference

0.196

388 - If the dilution factor is to low, the plaques will be

Plentiful

389 - If the eggs of male ZZ (Pogona vitticeps), when incubated in elevated temperature, these egg will produce

Female

390 - If there is no Guanine base in DNA double helix, the helix will forms

Both a and b

391 - If X chromosome and autosome ratio is equal to 0.5, the sex of fruit fly will be

Male

392 - If X chromosome and autosome ratio is equal to one, the sex of fruit fly will be

Female

393 - IIIS type of Diplococcus pneumoniae have characyeristic/s

All of these

394 - IIR type of Diplococcus pneumoniae have characyeristic/s

All of these

395 - In _________, the affected individuals have female external genitalia and internal ducts but have rudimentary ovaries

Turner syndrome

396 - In __________nuclear membrane reformed

Telophase1

397 - In 1927_______worked on virulent and avirulent strains of Diplococcus pneumoniae

Griffith

398 - In 1950, Cavalli-Sforza mutated E.coli K12 with nitrogen mustard into

Hfr

399 - In 1965, inosinic acid (I) was discovered by

Robert Holley

400 - In 1978,_________ reported the presence of telomere

Blackman

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