Home Genetics Genetics Most Important MCQs: Set#. 3

Genetics Most Important MCQs: Set#. 3

401 - In a cross between two T2 phages(hr+ x h+r), Which one is recombinant among the following progeny

hr

402 - In a cross between two T2 phages(hr+ x h+r), Which one is/are recombinant among the following progeny

Both b and c

403 - In a species such as E.coli, elongation proceeds at a rate of _________amino acids per second at 37áµ’C

15

404 - In abnormal human hemoglobin (Hb Bethesda), normal Try is substituted with__________β-145

His

405 - In abnormal human hemoglobin (Hb Mexico), normal Gln is substituted with__________α-54

Glu

406 - In abnormal human hemoglobin (Hb Saskatoon), normal His is substituted with__________β-63

Tyr

407 - In abnormal human hemoglobin (Hb Sydney), normal Val is substituted with__________β-67

Ala

408 - In abnormal human hemoglobin (Hb Toronto), normal Ala is substituted with__________α-5

Asp

409 - In abnormal human hemoglobin (HbJ Oxford), normal Gly is substituted with__________α-15

Asp

410 - In ABO blood group system, there are _____________different allele/alleles

3

411 - In all crocodiles, most turtle and some lizards, the sex determination is

TSD(Temerature dependent sex determination)

412 - In an experiment performed by Wollman and Jacob, after 10 minutes of bacterial conjugation, which gene got entry into recipient bacterium

azi

413 - In an experiment performed by Wollman and Jacob, after 15 minutes of bacterial conjugation, which gene got entry into recipient bacterium

ton

414 - In an experiment performed by Wollman and Jacob, after 20 minutes of bacterial conjugation, which gene got entry into recipient bacterium

lac

415 - In an experiment performed by Wollman and Jacob, after 25 minutes of bacterial conjugation, which gene got entry into recipient bacterium

gal

416 - In bacteria each Okazaki fragment contain about__________nucleotides

1000-2000

417 - In bacteria primer is replaced by

DNA polymeraseI

418 - In bacteria proofreading is function of

DNA Polymerase III

419 - In bacteria the monosome is a___________particle

70S

420 - In bacteria, genetic mapping is also called

Both a and b

421 - In bacteria, there is/are ___________releasing factor/factors

3

422 - In bacteria,the sequence of nucleotides AGGAGG on mRNA is called

Shine-Dalgarno sequence

423 - In birds, female is

Hetreogametic

424 - In birds, male is

Homogametic

425 - In boas and pythons, the sex chromosomes composition is

None of these

426 - In Caenorrhabditis elegans male is

X0

427 - In Caenorrhabditis elegans, if the ratio of X:A is 0.5, the sex will be

Male

428 - In Caenorrhabditis elegans, if the ratio of X:A is 1, the sex will be

Hermaphrodite

429 - In Caenorrhabditis elegans, normally there are male and ___________

Hermaphrodite

430 - In case of____________the presence of just one copy af allele results in the death of the individual

Dominant lethal allele

431 - In chlamydomonas str+mt+ x strsmt- , what will be the progeny

All str+

432 - In chlamydomonas strsmt+ x strsmt- , what will be the progeny

All str-

433 - In chlamydomonas there are _______mating types

2

434 - In conjugation process, the genes adjacent to__________ are transferred first

O

435 - In Danio rerio male is

None of these

436 - In Down syndrome about unusual ________characteristics are expressed

12 to 14

437 - In Drosophila melanogaster male is

XY

438 - In Drosophila, chaperones may function as

Heat -shock proteins

439 - In Drosophila, Males are_____________for sex linked genes

Hemizygous

440 - In Drosophila, only_________percent of the genome is occupied by genes coding for proteins.

10 to 15

441 - In Drosophilla, crossing over was shown to occur in_____________

female

442 - In E.coli the role of dnaB,C genes are to produce________at OriC

DNA helicase

443 - In E.coli the role of dnaE,N,Q,X,Z genes are to produce

DNA Polymerase III

444 - In E.coli the role of dnaG gene is to produce

RNA polymerase

445 - In E.coli the role of polA gene is to produce

DNA polymeraseI

446 - In E.coli the role of polB gene is to produce

DNA polynerase II

447 - In E.coli the role of repgene is to produce

DNA helicase

448 - In E.coli Type-I of topoisomerase reduces the_________supercoils into DNA

Negative

449 - In E.coli Type-II of topoisomerase introduces the_________supercoils into DNA

Negative

450 - In E.coli, elongation of transcription proceeds at the rate of________nucleotides/seconds at normal temperature

50

451 - In E.coli, there is only single replication origin called

oriC

452 - In early transformation studies, the effective length of transformed DNA was_________nucleotides

10000-20000

453 - In electrophoresis technique _________is used as medium

Agarose gel

454 - In Eukaryotes DNA ________ functions in repair of DNA single stranded breaks and the excision repair process

Lig 3

455 - In Eukaryotes DNA ________ is necessary for recombination and process called non-homologous end-joining

Lig 4

456 - In Eukaryotes DNA ________is the key ligase involved inDNA replication in mammalian cells

Lig 1

457 - In Eukaryotes each Okazaki fragment contain about__________nucleotides

100-500

458 - In eukaryotes the initial rRNA transcript is_______

45S

459 - In eukaryotes the monosome is a___________particle

80S

460 - In eukaryotes, sister chromatids are separated by

Topoisomerases

461 - In eukaryotes, many mRNAs contain a purine (A or G) three bases upstream from the AUG initiator codon is called

Kozak sequence

462 - In eukaryotes, the function of DNA polymerase alpha

RNA/DNA primer

463 - In eukaryotes, the function of DNA polymerase beta, theta and lambda

DNA repair

464 - In eukaryotes, the function of DNA polymerase delta

Lagging strand synthesis

465 - In eukaryotes, the function of DNA polymerase epsilon

Proof reading

466 - In eukaryotes, the function of DNA polymerase gamma

mtDNA replication

467 - In eukaryotes, the tail and cap of mRNA are held together with the help of initiation factor/factors

Both a and b

468 - In eukaryotes, there is/are ___________releasing factor/factors

1

469 - In eukaryotes, ubiquitin+misfolded proteins are digested by

Proteasome

470 - In eukaryotes,misfolded proteins are often tagged with small protein called

Ubiquitin

471 - In Eukaryotes,there is/are about________DNA ligase/ligses

3

472 - In Familial Down syndrome, one of the parent contains a

14/21

473 - In FMR1, the trinucleotide sequence _______is repeated in upstream region

CGG

474 - In fruit fly metamale and metafemale are

Infertile

475 - In fruit fly the sex determination is the control of

Both a and b

476 - In fruit fly, female with homozygous autosomal gene transformer(tra) will be

Sterile Male

477 - In fruit fly, male with homozygous autosomal gene transformer(tra) will be

Fertile Male

478 - In human _______carry two homologous x chromosomes

Metafemale

479 - In human abnormal sexual development(Klinefelter syndrome) has _________set of chromosomes

47, XXY

480 - In human abnormal sexual development(Turner syndrome) has _________set of chromosomes

45,X

481 - In human about_______million gametes are possible

8

482 - In human and many other species, there are________different aminoacyl tRNA synthetase

20

483 - In human arrested meiosis resumes in each oocyte just prior to its _________

Ovulation

484 - In human during oogenesis, the second division is completed only after_________

Fertilization

485 - In human inactivated X chromosome is also called

Both a and b

486 - In human intestinal cells APOB mRNA editing produces a single C to____change which converts a glutamine into a stop codon

U

487 - In human pattern baldness genotype BB will produce baldness in ___________

Male and female

488 - In human pattern baldness genotype Bb will produce baldness in ___________

Male

489 - In human pattern baldness genotype bb will produce baldness in ___________

None of these

490 - In human the telomeric sequence _____________repeated several thousand times

5-TTAGGG-3

491 - In human, about ________percent of human protein-coding genes have introns

94

492 - In Human, only_________percent of the genome is occupied by genes coding for proteins.

2

493 - In human, the probability of linkage in pedigree is calculated by__________method

Lod score

494 - In humans, the first division of all oocytes begins in the embryonic ovary but arrest in

Prophase1

495 - In inherited disorder(Tay-sachs), the patiant dies at the age of

3 year

496 - In leghorn breed, the feathering genotype__________has become fixed

hh

497 - In Lesh-Nyhan syndrome inherited as x-linked recessive disease, the nitogenous__________bases can not be salvage

Purines

498 - In Marfan syndrome in human dislocation of _________occurs

Lenses

499 - In meiosis chromosomes become short and thick in

Metaphase1

500 - In meiosis I spindle fiber attach with_________side/sides of kinetochore

One

501 - In meiosis II each gamete or spore receives_________chromatid/chromatids from each tetrad

1

502 - In meiosis II spindle fiber attach with_________side/sides of kinetochore

Both

503 - In meiosis nucleolus and nuclear membrane disappear in

Prophase1

504 - In Meselson and Stahl experiment the first generation of bacteria having heavy isotope of N during centrifuge will form band/bands in the______of test tube when grown in normal N containing medium

Middle

505 - In Meselson and Stahl experiment the second generation of bacteria having heavy isotope of N during centrifuge will form band/bands in the______of test tube when grown in normal N containing medium

Middle and top

506 - In Meselson and Stahl experiment the third generation of bacteria having heavy isotope of N during centrifuge will form band/bands in the______of test tube when grown in normal N containing medium

Middle and top

507 - In Meselson and Stahl experiment, which of the theory/theories could be ruled out after one round of replication

Cosevative

508 - In Meselson and Stahl experiment, which of the theory/theories could be ruled out after two rounds of replication

Dispersive

509 - In mitosis _______daughter cells are produced in one complete cell cycle

2

510 - In mitosis cohesin protein is degraded by an enzyme

Separase

511 - In molecular hybridization of nucleic acid DNA hybridize with________

Both a and b

512 - In most animals including humans, mtDNA cosists of

16-18 kb

513 - In most eukaryotes member of each species have________chromosomes in most of their cells

2n

514 - In most plant species, the Gametophyte is

Haploid

515 - In most plant species, the sporophyte is

Diploid

516 - In MST and PNT methods, the mtDNA is taken from

Donor

517 - In Musmusculus male is

XY

518 - In pedigree for human inheritance, circles represent

Female

519 - In pedigree for human inheritance, diamond represent

Sex unknown

520 - In pedigree for human inheritance, each generation is indicated by____________number

Roman

521 - In pedigree for human inheritance, fraternal or dizygotic twins, the sibling line is connected by_________line

Diagonal

522 - In pedigree for human inheritance, Identical or monozygotic twins, the diagonal lines are connected by_________line

Horizontal

523 - In pedigree for human inheritance, if parents are related, such as first cousins, are indicated by ___________line/lines

Double horizontal

524 - In pedigree for human inheritance, parents are indicated by single _______________line

Horizontal

525 - In pedigree for human inheritance, siblings are indicated by _______________line

Vertical

526 - In pedigree for human inheritance, sibs are placed in birth order from

Left to right

527 - In pedigree for human inheritance, squares represent

Male

528 - In pedigree for human inheritance, twins are indicated by _______________lines

Diagonal

529 - In pedigree for human, haded circles, squares and diamond represent_____________individuals

Affected

530 - In plants megaspore after germination produces

Female gametophyte

531 - In plants microspore after germination produces

Male gametophyte

532 - In Porphyria variegata , afflicted individuals can not adequately mrtabolize the

Porphyrin

533 - In Sacharomyces cervisiae, the gene fot mutant colony (petite) with small size colony locate on

Mitochondria

534 - In Sacharomyces cervisiae, the gene fot mutant colony (petite) with small size colony was discovered by

Ephrussi

535 - In Sacharomyces cervisiae, the mutant colony with small size is called

Petite

536 - In Seabright bantams breed, the feathering genotype__________has become fixed

HH

537 - In serial dilution minimum amount of sample required in ml

1

538 - In sickle cell anemia, valine was substituted for________ at the sixth position of the β chain

Glutamic acid

539 - In Somatic cell Hybridization, When a common cytoplasm contains different nuclei is called

Heterkaryon

540 - In Somatic cell Hybridization, When a different nuclei fuse together will form

Synkaryon

541 - In some eukaryotic genes, a cis-acting element within the core promoter is the __________

Both a and b

542 - In some eukaryotic genes, a cis-acting element within the core promoter is the TATA box, located about ______uncleotides pairs upstream

30

543 - In some reptiles_________ may has/have a great influenced on sex detrmination

Temperature

544 - In some_________RNA acts as genetic materia

Viruses

545 - In Temperature dependant sex determination, temoerature can not effect the follwing enzyme/hormone

Thyroxine

546 - In the 1960s, a new technique_____________proved to be successful in assigning genes to specific chromosomes

Somatic cell Hybridization

547 - In the bacteria, the DNA polymerase I is single polypeptide containing__________amino acids

928

548 - In the bacteria,the______is believed to be responsible for removing the primer and filling of gaps

DNA Polymerase I

549 - In the bacteria,which of the following enzyme is envolved in 5 to 3 polymerization

All of these

550 - In the bacteria,which of the following enzyme is/are complex

DNA Polymerase III

551 - In the glutamate receptor channels(GluR) mRNA editing Adenosine to __________editing occurs in mammalian brain tissues

I(inosine)

552 - In the peoples with phenylketonuria, blood level of phenylalanine is about_______mg/100ml

50

553 - In their initial experiments, Nirenberg synthesized________________ to decipher genetic code

RNA homopolymers

554 - In tissue culture dishes, normal human fibroblasts become senscent after about _________ cell divisions

50

555 - In vipers, the female is

Heterogametic

556 - In Xenopus laevis female is

ZW

557 - Increase in distance between two genes, __________the chance of parental gametes

Decreases

558 - Increase in distance between two genes, __________the chance of recombinant

Increases

559 - Increase in sample size, the average deviation from the expected results__________in Mendelian genetics

Decreases

560 - Individual bands are also called

Chromomeres

561 - Individuals having between________CGG repeat in FMR gene of fragile x syndrome(FXS) will be carrier

55-230

562 - Individuals having different genetic cell lines in somatic cells

Mosaics

563 - Individuals with mixture of karyotypes

Mosaics

564 - Initial phage density=( plaque number/mL x (______________)

Dilution factor

565 - Insertion/deletion editing in mRNA of trypanosomes is directed by

gRNA

566 - Interference ____________with increase in distance between two genes

Decreases

567 - Intersexuality is found in

Klinefelter syndrome

568 - Johan Mendel was born in

1822

569 - Klinefelter syndrome occurs in 1 of every female births

2000

570 - Klinefelter syndrome occurs in 1 of every male births

660

571 - Lactose intolerance is example of____________mutation

Nutritional

572 - Larger chromosome in trisomy condition cause_______ genetic imbalance in plants than smaller one.

Greater

573 - Less than________CGG repeat in FMR gene of fragile x syndrome(FXS) produce normal individuals

54

574 - Linear DNA is found in mitocondria of some

Ciliated protozoans

575 - LINEs costitute about_________percent of the human genome

21

576 - Lod score method was demonstrated by

Haldane

577 - Majority of ________fetuses die in uteri

45,X

578 - Mammalian cell contains____________of DNA polymerase molecules

20000-100000

579 - Mammalian genomes have as many as ____________replication origins

25000

580 - Many genes present on same chromosome, and they may indeed be transmitted as a single unit is called

Linkage

581 - Mapping in time units, in strain K12 is_______minutes long

100

582 - Maternal effect is due to herrdity of

Both a and b

583 - Mendel died of a________disorder

Kidney

584 - Mendel followed _________contasting traits in his experiments

7

585 - Mendel published his paper showing how traits were passed from generation to genration in

1866

586 - Mendel used the term of _________for allele

Factor

587 - Mendel's unit facrors represent units of inheritance called

Gene

588 - Microcephaly, cleft palate, Polydactyly and deformed finger nails are symptoms of

Patau

589 - Micronucleoli are found in the nucleus of

Oocyte

590 - Microsatellites appears throughout the genome approximately every________bases on average

10000

591 - Milk yield in dairy cattle is example of

Sex limited inheretance

592 - Milk yielding genses in dairy cattle are found in

Male and female

593 - Mirabilis jalapa variant have________leaves

All of these

594 - Misfolded proteins in bacteria are digested by

ATP dependent proteases

595 - Mitochondrial inheretance in Neurospora crasa was discovered by

Mary B Mitchel

596 - Mitochondrial ribosomes differ in size from______to_______

55-80

597 - Mitotic cells are fixed to slides and then subjected to hybridization is called _________molecular hybridization

In situ

598 - More than _________bacteriophage are produced per milliliter of culture medium

1010

599 - More than 90 percent of human ________cells contain telomerase activity

Cancer

600 - More than one polypeptide chains is characteristic of

Quarternary structure

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