Genetics Most Important MCQs: Set#. 4

601 - More than________CGG repeat in FMR1 gene lead to expression of fragile x syndrome(FXS)






230

602 - More than_______distinct mtDNA based genetic syndromes have been udentified






150

603 - Most of the genes on F factor are of ________genes






Tra

604 - MRT is used to treat_________diseases






mtDNA

605 - mtDNA is vulnerable due to






All of these

606 - Mullerian ducts differentiate into organs of _________reproductive tract






Female

607 - multiple alleles are found in






Population

608 - Mutations can alter






Both A and B

609 - Myotonic dystrophy(DMI) is the most type of _________muscular dystrophy






Adult

610 - Naturally___________arises ,when chromosomes replicate but cell does not divide






Polyploidy

611 - New large metacentric chromosome is produced during






Robertsonian

612 - No loss or gain of genes






Inversion

613 - Non functuional protein is produced due to






Null allele

614 - Noncoding nucleotides are absent in






Mitochondrial DNA

615 - Noncoding nucleotides are absent in






Both a and b

616 - Nondisjunction of homologous chromosome can produce






Aneuploidy

617 - NOR(Nuclear organizer region) is associated with






Nucleolus

618 - Normally genetic code is non overlapping but it may be overlapping in some_________






Viruses

619 - Now a days __________nucleotide pair length is considered most effective in gene cloning






2000

620 - Null allele produces______________Mutation






loss of function

621 - One codon contains__________ nucleotide/nucleotides






3

622 - One gene one enzyme hypothesis was presented by






Beadle and Tatum

623 - One in every ________humans either have a mtDNA based disorder






5000

624 - One in every_________newborn males is afflicted by Duchenne muscular dystrophy (DMD)






3500

625 - One map unit is equal to __________percent recombination between two genes






1

626 - One of the simplest statistical tests for assesing the goodness of fit of the null hypothesis is






Chi-square test

627 - One set of essential components of spliceosomes are






snRNAs

628 - Out of 64 codons___________codon do not specify any amino acid






3

629 - Overlapping in genetic code may be created due to___________initiation






Multiple

630 - Palindomes sequences of base pairs are present through out the ________region of Y chromosome






MSY

631 - Parents with contrasting traits may generate offspring with an intermediate phenotype is called_______dominance






Incomplete

632 - Partial monosomy occurs due to






Deletion

633 - Partiallly diploid recipient bacterium is also called






Merozygote

634 - Patau is ____________trisomy






47,13

635 - Patricia Jacobs discovered that 9 of 315 males in a Scottish maximum security prison had the___________karyotype






47, XYY

636 - Pattern baldness in humans is_______________trait






Sex influenced inheretance

637 - Pea plant is _____________






Self pollinating

638 - Phenotypic traits related to end product are often influenced by more than one _________






All of these

639 - Photosynthesis and respiration are example of






Metabolism

640 - Photosynthesis is example of






Anabolism

641 - physical maps are of____________types






3

642 - Plasmids contain_______gene/genes






Few

643 - Plasmids occur in _______copy/copies in the cytoplasm of bacterium






Multiple

644 - Point of origin(O) during conjugation is__________in different Hfr strains






Variable

645 - Poky, the slow growing mutant strain in Neurospora crasa is also designated as






mi-1

646 - Poky, the slow growing mutant strain in Neurospora crasa is crossed with wild type strain and the progeny was all Poky, Which one is maternal parent?






Poky

647 - Polar and negatively charged amino acid






Glutamic acid

648 - Polar and negatively charged amino acid






Aspatic acid

649 - Polar and positively charged amino acid/acids






All of these

650 - Poly A tail in mRNA transcripts is found in






All of these

651 - Poly A tails are associated with___________in bacteria






Degradation

652 - Poly A tails are associated with___________in eukaryotes






Protection

653 - Polyploidy is well known in






All of these

654 - Position of gene on chromosome is






Locus

655 - Premature aging may be due to mutation in genes responsible for






Telomerase

656 - Primary spermatocyte contain_________ in animals






2N

657 - Primer is synthesize by_________to start DNA synthesis






RNA polymerase

658 - Production of dark fur in certain body parts in Himalayan rabbits is due to_____________which is functional only at the lower temperature






Enzyme

659 - Proteins absob most strongly at






280nm

660 - Protruding and furrowed tongue, mouth partialy opened, physical and mental development retarded






Down syndrome

661 - Random fertilization is__________ in Mendelian genetics






Chance deviation

662 - Rapid growth of bacteria






log phase

663 - Rapid lysis (r) strain of viruses were discovered by






Alfred Hershey

664 - Rarely ____________ specify methionine during initiation






Both a and b

665 - Recombination in bacteria began in






1946

666 - Recombination of phage genomes take place by






Mixed infection of viruses

667 - Red blood cells posses ____________substance, to which terminal sugars are added






H

668 - Rediscoverer of Mendel work






Carl Correns

669 - Respiration is example of






Catabolism

670 - Restriction enzymes were discovered in






1970

671 - RF1 is specific to________termination codons






Both a and b

672 - RF2 is specific to________termination codons






Both a and b

673 - Rho binds to a specific sequence on the transcript known as






rut

674 - Runs in families






Down syndrome

675 - Scientist/s was/were interested in solving the structure of DNA






All of these

676 - Sedimentation behavior depends on a molecule's






All of these

677 - Self-excision is also involved in removal of introns from mRNA and tRNA transcripts of____________






Both a and b

678 - Serial dilution is step wise and _____________series of dilution






Geometrical

679 - Sex chromatin body was discovered by






Murray L. Barr

680 - Sex chromosomes in butterflies(Protenor) were identified by






Edmund B.Wilson

681 - Sex influenced traits are under the control of






Autosomal

682 - Sex limited traits are under the control of






Autosomal

683 - Sex pili are involved in process of






Conjugation

684 - Sickle cell anemia is caused by a mutation in






Hemoglobin

685 - SINEs costitute about_________percent of the human genome






13

686 - Sister chromatids are held together by multi-subunit protein complex called






Cohesin

687 - Slow growth of bacteria






Lag phase

688 - Somatic cell Hybridization was discovered by






Barski

689 - Somatic cells of eukaryotic organisms have ________set of chromosomes






2n

690 - Some genes on Y chromosome have homologous counter part on






X

691 - Some geneticists use the notation_________for female heterogametic






ZW

692 - Source of pollen (Green branch)x Location of ovule (white branch) will produce ________ branch progeny






White

693 - Source of pollen (Variegated branch)x Location of ovule (white branch) will produce ________ branch progeny






White

694 - Source of pollen (white branch)x Location of ovule (white branch) will produce ________ branch progeny






White

695 - Special array of chromosomes of an individual






Karyotype

696 - SRY gene is responsible for________sex determination






Male

697 - SRY gene locate on _______arm of Y chromosome






Short

698 - SRY gene missing, 46,XY will be






Female

699 - SRY gene reside on ___________region of MSY of Y chromosome






X-degenerative

700 - Stimulation of lytic cycle in prophage






Induction

701 - Streptomycin resistance In chlamydomonas may result from a mutation in______gene






Both a and b

702 - Substitution editing takes place in_________RNA






All of these

703 - Supercoiling in DNA was proposed by






Vinograd

704 - Tay-sachs disease, a recessive trait causes destruction of___________system






Nervous

705 - Tay-sachs disease, results from the loss of a single enzyme____________






Hexosainidase A(Hex-A)

706 - Telomerase was first discovered by






Blackman

707 - Temperatue sensitive mutant genes are common in Viruses, Bacteria and_________






Fungi

708 - Temperatue sensitive mutant genes produce functional product at__________






25áµ’C

709 - Temperatue sensitive mutant genes produce nonfunctional product at__________






42áµ’C

710 - Terminal sugars are absent in_________blood group






O

711 - Testis-determining factor(TDF) protein is under the control of_________gene






SRY

712 - Tetraploids grow more vigorously than do their_____________counterparts.






Both a and b

713 - The genetic variation in the gametes in an individual is result of






Crossing over

714 - The ÃŽ² pleated structure of protein is characteristic of






Secondary structure

715 - The ________ becomes the last part that can be transferred during bacterial conjugation






F factor

716 - The ________ contains one haploid set of chromosomes






All of these

717 - The ________ contains two complete haploid set of chromosomes






Zygote

718 - The _________ and coworkers provided the first insight into the molecular basis of sickle-cell anemia






Linus Pauling

719 - The _________ have been associated with autism, neurological disorders and cancer






Copy number variation(CNVs)

720 - The ____________ phenotypes are most easily recognized because they occur in the greatest proportion of offspring






Non crossover

721 - The _________cell wall/walls is/are deposited between cell membrane and middle lamella in each daughter cells






Both a and b

722 - The _________is responsible for fragile x syndrome(FXS)






FMR1

723 - The _________is wild type eye color






Brick red

724 - The ________coat color is dominant and homozygous recessive lethal in mice






Yellow

725 - The ________coat color is recessive lethal in mice






Yellow

726 - The ________coat color is wild type in mice






Agouti

727 - The ________gene/genes is/are under the control of Sex lethal(Sxl) gene for sex determination in fruit fly






Both a and b

728 - The 2,5-dihydroxyphenylacetic acid, also known as homogentisic acid can not be metabolized in patients with___________






Alkaptonuria

729 - The 20 kinds of amino acids are divided into_______major categories






4

730 - The 30 nm fibers are folded into a series of looped domains forming_________nm in diameter structure






300

731 - The A and B antigens are _____________group






Carbohydrate

732 - The ABO blood group phenomnon was discovered by






Landsteiner

733 - The acidic substance, isolated by Miescher from cell nuclei was named as






Nuclein

734 - The albinism in human is _____________trait






Recessive

735 - The allele that occurs most frequently in a population






Wild type allele

736 - The allele that produces an altered gene product






Mutant allele

737 - The alternate form of a gene






Allele

738 - The amplicon region of MSY is directly related to






Fertility

739 - The amplicon region of MSY is responsible for development of






Testes

740 - The area of human chromosome which fail to stain






Fragile sites

741 - The assembly of mature bacteriophages was studied by






Willium Hood

742 - The average half life for mRNAs in cultured human cells is________hour






10

743 - The bacteria that contain toxic proteins for other bacteria are also called as






Colicinogenic

744 - The bacteria that have ability to take ip foreign DNA are called ________bacteria






Competent

745 - The bacteria whose cell wall is removed enzymeticaly are called






Both a and b

746 - The bacterial cell is ruptured by________enzyme(a phage gene product)






Lysozyme

747 - The bacterial RNA transcripts lack____________






Both a and b

748 - The bacterial start codon is recognized by an intiator tRNA carrying a ______________






N-formylmethionine

749 - The bacteriophage lambda possesses a ___________DNA molecule after infection






Circular double stranded

750 - The bacteriophage lambda possesses a ___________DNA molecule prior to infection






Linear double stranded

751 - The bacteriophages have ____________sensitive mutations






Temperature

752 - The Bar eye phenotype in Drosophila is examlpe of






Duplication

753 - The Bar eye phenotype in Drosophila was discovered by






Sturtevant

754 - The Barr body orignate from __________ X chromosome






Random

755 - The bases of opposite chains are held together by _______bond






Hydrogen

756 - The brachydactyly in human is _____________trait






Diminant

757 - The C-_____atom of the sugar is involved in the chemical linkage to the nitrogenous base






1

758 - The C-1 atom of the sugar is involved in the chemical linkage to the nitrogenous base at N-_____if the base is purine






9

759 - The C-1 atom of the sugar is involved in the chemical linkage to the nitrogenous base at N-_____if the base is pyrimidine






1

760 - The catalytic steps that joins amino acids during translation are under the control of






rRNA

761 - The cDNA sequences are complmentary to






mRNA

762 - The cell cycle is the controlled by__________






All of these

763 - The cell furrow is the characteristics of newly divided cells of________cells






Animals

764 - The cell plate laid down across the metaphase plate in dividing___________cells






Plants

765 - The cell which has membrane bounded nucleus






Eukaryotic

766 - The cell which has no membrane bounded nucleus






Prokaryotic

767 - The chance of an event to occur






Probabilties

768 - The chances of Down syndrome increases with the increase in age of






Mother

769 - The chances of occurance of phenyketonuria is____in 20000 births in United States






1

770 - The change in position of gene






Translocation

771 - The chaperones are found in






All of these

772 - The chloroplast DNA (cpDNA) range in size






100-225 kb

773 - The chromosomal abberrations can alter the






All of these

774 - The chromosomal theory of inheritance was formulated by






Sutton and Boveri

775 - The chromosomes begin to uncoil once again during division of cells






Telophase

776 - The codon for methionine






AUG

777 - The codon that do not specify any amino acid is called






All of these

778 - The Col plasmids also contain genes for_________along with toxicity for other bacteria






Immunity

779 - The Col plasmids contain genes for






Toxicity for other bacteria

780 - The color blindness in human is _____________trait






Recessive

781 - The color of homogentisic acid is _______which is excretedcin the urine






Black

782 - The commercial strawberry is






Octaploid

783 - The complete haploid DNA content of a specific organism are called






Genomic libraries

784 - The condensed and inactive part of chromosome is called






Heterochromatin

785 - The condition in which cell cease to divide






Senescence

786 - The constriction of cytoplasm occur across the metaphase plate in dividing___________cells






Animals

787 - The cortex of gonadal ridges gives rise____________during human development






Ovary

788 - The cri du chat is example of






Deletion

789 - The cri du chat results due to missing of _______gene






TERT

790 - The cri du chat results, when the small terminal portion of chromosome_______is lost






5

791 - The cross involved only one pair of contrasting traits






Monohybrid

792 - The cytokinesis takes place at the end of






Telophase

793 - The cytolpsmic transfer is used to treat_______disorder






mtDNA

794 - The cytoplasmic mutation in streptomycin is






Uniparental

795 - The darkness of ear and nose due to accumulation of homogentisic acid is symptom of






Alkaptonuria

796 - The degradation of large molecules into small molecules and the synthesis of large molecules from small molecules is called






Metabolism

797 - The degradation of large molecules into small molecules is called






Catabolism

798 - The degree of freedom(df) in statistical analysis is






n-1

799 - The delivery of proteins to its proper location is functuion of






Target peptides

800 - The detail map of rII in phage T4 was represented by






Benzer

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