Genetics Most Important MCQs: Set#. 5

801 - The development of genetic markers and a mapping_______ are essential in genetic map






Population

802 - The development of hardware and software for processing nucleotides and protein data is called






Bioinformatics

803 - The dilution factor______ will lyse the entire lawn of bacteria






44837

804 - The distance between A_B gene is 3 mu and distance between B_C is 2 mu,What will be the percentage of expected frequency of double crossover






0.06

805 - The distance between genes is measured in






Both a and b

806 - The distance between two genes is measured in






Both a and b

807 - The distinct form of SRGP2 labeled A-D appeared about _______million years ago






1

808 - The DNA in Chloroplast and Mitochondria have resemblance with DNA of






Bactria

809 - The DNA in E.coli chromosome is __________µm long






1200

810 - The DNA in each human chromosome ranges from_________






19000-73000

811 - The DNA of Bacteriophage contains more than________genes






150

812 - The DNA sequences such as cis-acting elements locate/at_______ region to be transcribed






Near

813 - The double helix has a diameter of_________angstrom






20

814 - The doubling time during the log phase can be as short as






20

815 - The Down syndrome trisomic 21 can be contributed from






Both a and b

816 - The Dystrophin gene, a 2400 kb gene containing________exons






79

817 - The E.Coli haploid genome consists of __________percent rDNA






0.7

818 - The earliest synthesized RNA runs through a groove in the enzyme called as






Lid

819 - The energy used in initiation of translation






GTP

820 - The enhancers and silencers along with promoters are found in________genes






Eukaryotic

821 - The enzyme responsible for deamination of adenosine to produce inosine during mRNA editing






ADAR

822 - The enzyme responsible for the synthesis of H substance






Fucosyl transferase(FUT1)

823 - The enzyme reverse transcriptase is resonsible for synthesis of ________________






RNA to DNA

824 - The enzyme_________synthesizes artificial RNA templates






Polynucleotide phosphorylase

825 - The equatorial plane is the _________region of the dividing cells






Middle

826 - The exchange of segments of non sister chromatids during meiosis






Crossing over

827 - The exon shuffling may be the cause of___________genes






Evolution

828 - The exon shuffling may occur due to






Both a and b

829 - The exon shuffling may occur due to






All of these

830 - The exon shuffling, the model for the evolution of genes was presented by






Walter Gilbert

831 - The expected frequency of double crossover gametes often remains___________than that of single crossover






Lower

832 - The expression of genes on one homology, but not the other homology is called






Imprinting

833 - The expression of Sex limited and esx inluenced traits are under the control of






Hormones

834 - The ezymology of DNA replication was first reprted by






Kornberg

835 - The F factor plasmids contain genes for






Sex pilus

836 - The factor/factors that stabilizes/stabilize the DNA double helix






All of these

837 - The factor/factors that stabilizes/stabilize the DNA double helix






All of these

838 - The failure of sex chromosomes to segregate during meiosis






Nondisjunction

839 - The fibroin, the protein made by the silk moth, depends extensively on






ÃŽ² pleated

840 - The first amino acid to be fixed in protein synthesis






Methionine

841 - The first chromosome-banding technique was devised by






Mary-Lou Pardue

842 - The first cytoplasmic mutation streptomycin was reprted in __________






Chlamydomonas

843 - The first cytoplasmic mutation streptomycin was reprted in chlamydomonas by






Rath Sager

844 - The first direct evidence that one gene one protein was confirmed from study of____________






Sickle cell anemia

845 - The first experimental evidence that genes are responsible for the synthesis of enzymes was proved by






George Beadle

846 - The first exposed DNA during replication process is called






ssDNA

847 - The first genetic map was constructed by






Sturtevant

848 - The first layer formed between two daughter cells in plants is






middle lamella

849 - The flower and fruit size increases in






Autopolyploids

850 - The folding of proteins may take place with the help of






Chaperones

851 - The formula for coefficient of coincidence is






Observed DCO/Expected DCO

852 - The formula for Interference is






1-C( coefficient of coincidence)

853 - The fragile x syndrome(FXS) can cause ________retardation






Mental

854 - The fragile x syndrome(FXS) more common in






Male

855 - The framshift mutation becomes a stop codon in






All of these

856 - The frequency of __________between any two loci on a single chromosome is proportional to the distance between them






Crossing over

857 - The frequency of crossover between A-C 30%, B-C 45%, B-D 40% and A-D is 25%, What wii be the genes sequence






BADC

858 - The fruit fly haploid genome consists of __________percent rDNA






0.3

859 - The gaps between Okazaki fragments are sealed with the help of






DNA ligase

860 - The gaps left at the 5 ends of the newly synthesized DNA are filled by






Telomerase

861 - The gene autosomal gene transformer(tra) responsible for sex detrmunation in fruit fly was discovered by






A.H. Sturtevant

862 - The gene for ADA immune deficiency is located on________chromosome






20

863 - The gene for Alzheimer disease is found on_________chromosome






Chromosome no.14

864 - The gene for azoospermia is located on________chromosome






y

865 - The gene for Breast cancer is found on






Chromosome no.17

866 - The gene for cystic fibrosis is located on________chromosome






7

867 - The gene for familial hypercholesterolemia is located on________chromosome






19

868 - The gene for Melanoma disease is located on________chromosome






9

869 - The gene for muscular dystrophy is located on________chromosome






x

870 - The gene for Phenylketonuria(PKU) disease is located on________chromosome






12

871 - The gene for polycystic kidney disease is located on________chromosome






16

872 - The gene for Retinoblastoma disease is located on________chromosome






13

873 - The gene for Sickle-cell Anemia is located on________chromosome






Chromosome no.11

874 - The gene for Tay-sachs disease is located on________chromosome






15

875 - The gene/genes coding for ___________a signaling protein of the immune system has/have no introns






Both a and b

876 - The gene/genes in which the three nucleotides is repeated (trinucleotide repeats) many time






All of these

877 - The genes for the A and B antigens locate on chromosome






9

878 - The genes IA and IB are example of






Codominance

879 - The genes that are not transcribed due to insertions and deletions throughout their structure






Pseudogenes

880 - The genes that code for rRNA are located in an area of chromosome known as






NOR(Nuclear organizer region)

881 - The genetic code containing triplet base was proposed by






Brenner

882 - The genetic code was deciphered by






Nirenberg

883 - The genetic consequences of reciprocal translocation are similar to






Inversion

884 - The genetic constitution of cri du chat is






46,5p-

885 - The globular structure of proteins is characteristic of






Tertiary structure

886 - The glutamate receptor channels(GluR) mRNA editing occurs in mammalian_______tissues






Brain

887 - The gonads development in mammals is under the control of






Double sex (dsx)

888 - The gray body color which is wild in nature is represented by






e+

889 - The group of enzymes that cut one or both of the strands and wind or unwind the helix before resealing the ends






Topoisomerases

890 - The gut cells (16n) of Mosquito larvae undergo reduction divisions, giving rise to smaller_________cells






Diploid

891 - The gut cells of Mosquito larvae may attain a






16n

892 - The H substance contains three sugar molecule, Galactose, N-acetyllgalactosamine and






Fucose

893 - The half life of mRNA of bacteria is________minutes






5

894 - The haploid genome of human contains more than ________bilion base pairs of DNA






3

895 - The haploid number (n) is equal to _________the diploid number






One-half

896 - The haploid number of chromosomes for fruit fly(Drosophila melanogaster)






4

897 - The haploid number of chromosomes for champanzee






24

898 - The haploid number of chromosomes for corn(Zea mays)






10

899 - The haploid number of chromosomes for cotton(Gossypium hirsutum)






26

900 - The haploid number of chromosomes for dog(Canis familiaris)






39

901 - The haploid number of chromosomes for garden pea(Pisum sativum)






7

902 - The haploid number of chromosomes for House mouse(Mus musculus)






20

903 - The haploid number of chromosomes for human(Homo sapiens)






23

904 - The haploid number of chromosomes for pink bread mold(Neurospora crassa)






7

905 - The haploid number of chromosomes for round worm(Caenorhabditis elegans)






6

906 - The haploid number of chromosomes for wheat(Triticum aestivum)






21

907 - The haploid number of chromosomes for yeast(saccharomyces cerevisiae)






16

908 - The haploid number of chromosomes for zebrafish(Danio rerio)






25

909 - The Head of Bacteriophage is






Icosahedron

910 - The helix structure of DNA was confirmed by






Franklin

911 - The hemophilia in human is _____________trait






Recessive

912 - The Hepatitis C disease in human is ____________trait






None of these

913 - The hereditary deafness is example of






Both a and b

914 - The heritable disorder that exhibit a progressively earlier age of onset is called genetic___________






Anticipation

915 - The heteroduplex region of DNA is found after






Transformation

916 - The highly repetitive ______________DNA is localized in the centromere regions of mice






Satellite

917 - The human adult hemoglobin contains two identical ÃŽ± chain of_______amino acids






141

918 - The human adult hemoglobin contains two identical ÃŽ² chain of_______amino acids






146

919 - The human genome contains genes that encode at least_______different DNA polymerases






14

920 - The humans have at least _____________copy/copies of SRGAP2






4

921 - The Huntington disease in human is _____________trait






Diminant

922 - The Huntington disease is due to ___________autosomal allele






Dominant lethal allele

923 - The Huntington disease trigers in the age of






40

924 - The hypercholesterolemia in human is _____________trait






Diminant

925 - The hypothetical portion of called DSCR is found in






Down syndrome

926 - The ÃŽ± helix structure and ÃŽ² pleated structure are stabilized by






Hydrogen bond

927 - The ÃŽ± helix structure of protein is characteristic of






Secondary structure

928 - The idea of spontanous generation was disproved by






Louis Pasteur

929 - The identification of introns in eukaryotic genes involves a direct comparison of nucleotide sequences of DNA with those of _______






mRNA

930 - The incidence of cri du chat woeldwide is 1 in _________live births






25000-50000

931 - The individuals whose phenotype first brought attention to the family is called






Proband

932 - The infants with cri du chat suffer from gastrointestinal malfunctioning, cardiac complications and abnormal development of






Glottis and larynx

933 - The information encoded in mRNA is






Codon

934 - The inhibition of further crossover events by a crossover event in a nearby region of the chromosome is called






Interference

935 - The initial amino acid in all polypeptide chains is __________






Methionine

936 - The initial amino acid methionine is formylated in_________






Bacteria

937 - The initial amino acid methionine is unformylated in_________






All of these

938 - The initial rRNA transcript in bacteria is






30S

939 - The insertion of Pyrrolysine into polypeptides require/requires_________codon/codons which normally funtion as stop codon






UAG

940 - The insertion of Selenocysteine into polypeptides require/requires_________codon/codons which normally funtion as stop codon






UGA

941 - The integrated bacterial DNA with viral DNA






Prophage

942 - The interval between division of cell






Interphase

943 - The intial results were discouraging because of ___________haploid number of human chromosomes






High

944 - The intron which is itself the source of the enzymatic activity necessary for splicing is called






Ribozyme

945 - The introns in eukaryotes help in






All of these

946 - The kinetochore is located on






Both b and c

947 - The large subunit of Rubisco is encoded by






Chloroplast DNA

948 - The length of major groove is __________angstrom






22

949 - The length of minor groove is __________angstrom






12

950 - The length of target peptides, which function like postal codes for the cells






3-7 amino acids

951 - The Lesh-Nyhan syndrome inherited as x-linked recessive disease is characterized by abnormal ____________metabolism






Nucleic acid

952 - The location of a gene on chromosome






Locus

953 - The location of RNA polymerase I (RNAP I) in eukaryotes






Nucleolus

954 - The location of RNA polymerase II (RNAP II) in eukaryotes






Nucleoplasm

955 - The location of RNA polymerase III (RNAP III) in eukaryotes






Nucleoplasm

956 - The long interspersed elements(LINEs) are less than 6kb base pairs long and may be present____________times in the human genome






850000

957 - The longer arm of chromosome shown below the centromere is known as






q arm

958 - The lysine replaces glutamic acid in






HbC

959 - The major components of chromosomes are DNA and________






Prptein

960 - The manifestation of mutant phenotype is the result of internal_____________environment of an organism changing during development and age






Physiological

961 - The manipulation of foreign genes into host genome is called






All of these

962 - The Marfan syndrome in human is example of






Pleiotropy

963 - The master switch in sex determination in fruit fly is






Sex lethal (Sxl)

964 - The mating partner/partners in chlamydomonas






Both a and b

965 - The mean onset of Huntington disease is__________years






38

966 - The medulla of gonadal ridges gives rise____________during human development






Testis

967 - The membrane bounded cell organelles are present in






Both b and c

968 - The Meselson and Stahl used ____________in the growth medium to grow bacteria






Ammonium chloride

969 - The Meselson and Stahl used isotopes of ____________in the growth medium to grow bacteria






N

970 - The Meselson and Stahl used salt of ____________in the test tube for sedimentation equilibrium centrifugation






Cesium chloride

971 - The methylation of histones have ____________imact on gene activity






Both a and b

972 - The mice coat color gene reside on






X

973 - The microRNA(miRNA) is involved in






Regulation of gene expression

974 - The migration of centrioles to opposite ends of cell takes place in






prophase

975 - The misfolded proteins can cause






Scrapie in sheep

976 - The misfolded proteins can cause






All of these

977 - The mitochondria and chloroplast arose about 2 billion years ago from






Protobacteria

978 - The MN blood group in human is example of






Codominance

979 - The MN blood group phenomnon was discovered by






Landsteiner

980 - The MN blood group system is under the controle of a locus found on chromosome






4

981 - The mode of action of antibiotic(Chloramphenicol) in bacteria






Inhibits peptidyl transferase

982 - The mode of action of antibiotic(Erythromycin) in bacteria






Inhibits formation of 70S ribosome

983 - The mode of action of antibiotic(Kasugamycin) in bacteria






Inhibits binding of tRNA f-met

984 - The mode of action of antibiotic(Streptomycin) in bacteria






Bind to 30S Ribosomal subunit

985 - The mode of action of antibiotic(Tetracycline) in bacteria






Inhibits Chaeged tRNA

986 - The mode of action of antibiotic(Thiostrepton)






Inhibits EF-G

987 - The mode of sex determination in fruit fly can be explained by____________theory






Geneic balance

988 - The mode of sex determination in fruit fly was discovered by






Bridges

989 - The mode of transmision of streptomycin in chlamydomonas is under the control of






mt+

990 - The model organism C. elegans is used to study






Diabetes

991 - The model organism D.rerio is used to study






Cardiovascular disease

992 - The model organism E.Coliis is used to study






Cancers

993 - The model organism M. musculus is used to study






Cystic fibrosis

994 - The modified mRNA in eukaryotes has/have






All of these

995 - The modified versions of cysteine (Sec) is found in






All of these

996 - The more rigid and water insoluble proteins, usually contain a ________structure






ÃŽ² pleated

997 - The most common methods for MRTs are MST and _______






PNT

998 - The most commonly used Cas nuclease is






Cas9

999 - The mRNA editing in cold temeratures is ________depentant potasium channel in cephalopod






Voltage

1000 - The MSY contais____________region/regions






All of these

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